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二 | Kareena Kapoor Khan has been one of Bollywood’s most beloved actresses for over two decades. She made her debut in 2000 opposite Abhishek Bachchan in Refugee and has since captivated audiences with a wide range of performances. From romantic comedies to intense dramas, the actress has delivered roles that are not only memorable but have also become a part of Bollywood's pop culture. Here’s a look at some of her unmissable films that showcase her range and talent. In This Article Refugee (2000)Kabhi Khushi Kabhie Gham (2001)Chameli (2004)Omkara (2006)Chup Chup Ke (2006)Jab We Met (2007)Heroine (2012)Udta Punjab (2016)Crew (2023)Refugee (2000) Kareena Kapoor made her Bollywood debut with Refugee alongside Abhishek Bachchan. The film, directed by JP Dutta, tells the story of two young people caught in the complex world of human trafficking along the India-Pakistan border. The actress played Nazneen, a spirited and determined young woman who falls in love with Abhishek’s character, known as 'Refugee'. He helps illegal refugees from India and Pakistan cross the border through the Great Rann of Kutch. Even as a debutant, her performance was confident and graceful, and the actress won the Filmfare Award for Best Female Debut. Kabhi Khushi Kabhie Gham (2001) Karan Johar's Kabhi Khushi Kabhie Gham remains one of Kareena Kapoor’s most iconic films. She played the effervescent Pooja, also known as Poo. The actress' portrayal of the stylish and confident Poo became instantly memorable and is still celebrated today. The film featured an ensemble cast including Shah Rukh Khan, Amitabh Bachchan, Jaya Bachchan, Hrithik Roshan, and Kajol. Her comic timing, style, and energy made Poo a character that defined a generation of Bollywood fashion and pop culture. Chameli (2004) Chameli was a turning point in Kareena Kapoor's career, where she took on a much darker and unconventional role. She played Chameli, a street-smart sex worker, opposite Rahul Bose in a rain-soaked, single-night narrative. Her performance was intense and emotionally grounded, showcasing a depth rarely seen in her earlier work. The actress won the Special Award for Best Performance at the Filmfare Awards. Omkara (2006) Omkara is Vishal Bhardwaj’s adaptation of Shakespeare’s Othello. Kareena played Dolly, a loyal and innocent woman caught in a story of jealousy, betrayal, and tragedy. She starred alongside Ajay Devgn, Saif Ali Khan, Vivek Oberoi and Konkona Sen Sharma. Kareena delivered a nuanced performance that suited the dark and complex narrative. She won the Filmfare Award for Best Actress (Critics) for Omkara. Chup Chup Ke (2006) Chup Chup Ke is a comedy-drama directed by Priyadarshan, in which Kareena Kapoor plays Shruti Singh Chauhan, a young woman who is mute and becomes central to the film’s twists and comic moments. The story follows Jeetu (Shahid Kapoor), a debt‑ridden young man who, overwhelmed by financial pressure, decides to fake his own death to help his family claim insurance money. Rescued by two fishermen who mistakenly believe he is mute and wealthy, Jeetu begins pretending not to speak or hear to maintain the misunderstanding. This leads him to the household of Shruti and her affluent family. The film also stars Suniel Shetty, Neha Dhupia, Paresh Rawal, Rajpal Yadav and Om Puri among others. Jab We Met (2007) Jab We Met remains one of Kareena’s most beloved films. In the Imtiaz Ali directorial, she played Geet, a lively, talkative, and spirited young woman who meets a heartbroken businessman, Aditya (played by Shahid Kapoor), on a train journey. Their interaction changes the course of both their lives. Her charm, energy, and comic timing were effortless, and the character became iconic in Bollywood cinema. Kareena’s dialogues and looks from the film have become a part of the pop culture. Heroine (2012) Madhur Bhandarkar's Heroine saw Kareena play Mahi Arora, a once-successful actress whose personal life and career are on the decline. To bring her career back on track, she hires a public relations manager, who uses sensationalist tactics to keep Mahi in the spotlight. However, certain events and life-changing controversies led to her quitting the film industry. The film explores the pressure of stardom, the reality underneath the glamour and the emotional toll of living in a world where public image means everything. While it received mixed reviews, Kareena's performance was lauded by fans and critics. Heroine also starred Arjun Rampal, Randeep Hooda, Divya Dutta, Govind Namdev and Sanjay Suri among others. Udta Punjab (2016) In Udta Punjab, Kareena Kapoor took on a socially relevant role as Dr Preet Sahni, a compassionate doctor working to combat drug abuse in Punjab. The film, also starring Shahid Kapoor, Alia Bhatt, and Diljit Dosanjh, addressed a pressing societal issue. Crew (2023) Crew, directed by Rajesh A Krishnan, is a heist comedy where Kareena Kapoor Khan stars alongside Tabu and Kriti Sanon as three flight attendants who work for a struggling airline. When the trio accidentally uncovers a gold-smuggling operation on one of their flights, they decide to turn the tables and devise a dangerous plan to outsmart the criminals and secure the treasure. The film blends comedy, suspense, and teamwork. Kareena’s performance balances charm and comic timing with a sense of cleverness, making her a standout in this female-led ensemble. Also Read: Kareena Kapoor Khan Teases Meghna Gulzar With a Fun Travel Update From Daayra Shoot。此前,白血病被公认为全球性的难治之症。张晓辉介绍,不同类型白血病的治疗现状有所不同。

三 | 若确诊为慢性粒细胞白血病,该疾病已走向慢性病管理模式。随着靶向治疗药物的问世,大多数慢性粒细胞白血病患者已实现治愈,能够重返社会和工作岗位。
对于急性白血病,张晓辉指出可通过靶向药物治疗、精准化疗、造血干细胞移植以及以 CAR-T 为代表的细胞治疗新手段实现可控可治。以急性早幼粒白血病为例,中国原创的“上海方案”通过“维甲酸 + 砷剂”联合治疗方案,已帮助绝大多数患者康复并恢复正常生活水平。在造血干细胞移植治疗白血病领域,中国提出的“北京方案”实现了人人都有移植供者,突破了供者来源受限的世界性难题,使中国在该领域从技术跟跑、并跑迈向领跑。

四 | IT之家注:CAR-T 即嵌合抗原受体 T 细胞免疫疗法,是一种通过改造患者自身免疫细胞来识别并攻击癌细胞的精准治疗技术。

五 | 张晓辉强调,中国在造血干细胞移植领域处于世界前沿,大多数患者能够在技术条件完备的医疗体系下得到有效治疗。对于难治性患者,医生可综合运用多种治疗手段和技术帮助其康复。他呼吁公众,若不幸确诊白血病,应正确面对、及时就医,通过医患积极沟通推动疾病走向治愈。

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